Abstract
This paper digs deeply into how aspirin and salbutamol were developed and also how they interact in the body from a heavy chemical and neurological perspective. It also gives a detailed overview into how, in general, pharmacueticals are developed using bronchodilars as an example. Also included are numerous diagrams in order to aid the reader comprehend the text.

From the Paper
"Since 400BC physicians prescribed a bitter powder extract from the willow bark tree to alleviate pain. In the middle of the 18th century two chemists by the name of Fontana and Brugnatelli extracted the active agent Salicin from the willow, and was then converted by Piria into Salicylic acid. Felix Hoffman a German chemist set about trying to synthesize salicylic acid."

Tags:adrenaline, adrenocepters, agonist, bark, compound, cox1, cox2, hoffman, industry, kolbe, meloxicam, pharmaceutical, phenol, salicylic, ventolin, willow

Abstract
This paper begins with an articulation of origins and developments of transformational leadership theory and while supporting the assertion that charisma is an important component of transformational leadership behaviour argues that it is not in itself a defining feature. The cascading effect of transformational leadership is explored in relation to contemporary research both within the U.S. and U.K. and is utilised to articulate the relationship between transactional and transformational behaviours within health care settings which constitute an optimum change profile. The nature of vision and charisma within the health care setting are critically evaluated along with the relationship between transformational leadership and key outcomes such as felt autonomy, job satisfaction, low staff turnover, service quality and the achievement of organisational (cultural) change.

Outline
Abstract
Transformational Leadership
Explanation of Transformational Leadership Behaviours
A Full Range Model of Transformational Leadership
Criticisms of Transformational Leadership Theory
Charismatic Leadership
Personal Identification
Social Identification
Internalisation
Self-Efficacy
Facilitating Conditions
Criticisms of Charismatic Leadership Theory
Summary

From the Paper
"Bass (1985, 1998) provides a more expanded and refined theory of transformational leadership which develops the work of Burns (1978) and House (1977), by giving far more attention to the behaviour and needs of followers than had previously been given. Bass (1985, 1998) argued that the principles of transformational leadership could be equally applied to situations where the outcomes were not positive than those where the opposite was true and describing transactional and transformational leadership as a singe continuum rather than mutually independent continua. Bass (1985, 1998) identifies the main characteristics of transformational leadership as; charisma idealised influence, intellectual stimulation and consideration of the emotional needs of each follower, (Hunt, 1996)."

Tags:innovation, integration, autonomy

Abstract
This paper examines how mycobacterium tuberculosis is a very efficient pathogen with a uniquely successful method of pathogenicity. It describes why it is an excellent pathogen, features of a tuberculosis infection and looks at social and economic impacts. Treatment and control programmes are also mentioned. Although a number of control programmes have been developed to help eradicate the organism, there is no definitive answer to the major endemic.

From the Paper
"Mycobacterium tuberculosis does not produce toxins but it does however have a number of virulence factors that enable it to successfully infect a host. Cord factor (trehalose dimycolate) found in the cell wall is toxic and has both adjuvant and granuloma inducing properties, it also non-specifically activates macrophages.
The presence of secondary hydroxamates, which are iron-chelating agents, in the cell wall allows the bacteria to utilise the host's iron. The waxy outer capsule allows Mycobacterium tuberculosis to survive in air and dust for a long time, which contributes to the problems associated with eradicating this organism."

Tags:bacteria, disease, immunisation, pathogen, virulence

Abstract
This paper provides a case study of young African man who was brought into A&E by the ambulance crew. The main theory that underpins the whole assessment process is the Roper- Logan-Tierney Model by Roper et al (1996), popularly known as the Roper's model, which emphasises the interaction between biological, psychological and social factors as influences on human behaviour and therefore, on health.

Outline
Background and Context of the Patient
The Assessment Process
The History of the Presenting Problem
Nursing Management Priorities
Conclusion

From the Paper
"The history of the presenting problem was collected from the statements and the documentation of the paramedics as well as by directly asking the patient. In many cases the patient was asked to confirm the details. This was good as the patient was actively included in the process. The paramedic said that they had been called to the patient's address as the patient was a having a progressive headache and that it was so bad that he could not function in any way, let alone, drive to the A&E department."

Tags:holistic, model, roper, systems, theory, tierney

Abstract
This paper argues that the relationship between an environment and its diseases that occur within it are not static over time. The paper discusses infectious diseases, non-vectored diseases, and deficiency diseases. AIDS is given as an example of how a disease that was once a major problem in North America is now a major problem in Africa.

From the Paper
"Diseases occur in all parts of the world. However, different groups of people will be vulnerable to different diseases at different times, depending on where they are in the world - or rather, what environments they are in. The term used to investigate the relationship between diseases and the environments in which they occur is known as Disease Ecology. Disease Ecology can be a reference to diseases within the natural environment, but also to diseases that occur within manmade environments, mainly cities. There are many different types of diseases that could be investigated here. This essay will look at diseases in both the natural and man-made environments. These will include Deficiency diseases, Infectious diseases, Chronic diseases and Social diseases."

Tags:infectious, disease, ecology, aids, manmade, environment, non-vectored, africa, north, america, chronic, social, cholera

Abstract
This paper provides insight into anorexia nervosa, a mental illness where individuals refuse to eat in pursuit of losing weight due to their intense fear of being fat. It looks at the two types of anorexia nervosa, the primary and secondary form and examines some of the physical symptoms that patients incur such as pallor, emaciation, weakness, muscle fatigue, lanugo (a growth of fine body hair) and amenorrhoea as well as heart complications. It looks at how there are several psychological models which can describe anorexia and focuses on the cognitive model and the behaviorist model. It shows how behavioral therapies are based on the assumption that mental disorders are maladaptive behaviors which have resulted from faulty learning and how the cognitive model concerns itself with the internal processes of thought and the role played by expectations, attitudes and the interpretation of events.

From the Paper
"Anorexia nervosa is not the result of an overnight decision. This is why it is so difficult to become aware of until it has advanced to a substantial degree. It generally starts off as a harmless diet, usually without the intentions to starve oneself. In spite of that, if a person has certain predispositions, it may gradually result in anorexia. This is because as the diet progresses, the individual may experience some kind of "dieting euphoria" because this kind of lifestyle provides them with a sense of control for two reasons; an external and an internal. The external reason is that it provides a sense of "mastery and euphoria to a person who previously not only felt weak but depressed and empty" (Richard A. Gordon). And the internal reason is the accomplishment of a thin body is appraised by today's society. However the feeling of euphoria that is experienced is relatively short-lived. In fact, the longer the fasting lasts, a sense of depression gradually takes over to the degree where it becomes a dominant mood. Eventually, the anorexic will go to any extremes in order to conceal and defend her low weight and minimum appetite."

Tags:disorders, psychology, treatments, diet, mental

Abstract
This research proposal explores the disease of asthma, its symptoms, affected populations, and treatments, with particular focus on the usefulness and efficacy of nutritional supplements. The role of the FDA is touched upon, and the hypotheses and methodology for the proposed study are included. The paper concludes that possibly, if a study is undertaken with regards to nutritional supplements usage and the treatment of asthma in elderly and adult patients, effects can be noted and a base for further research can be developed.

Outline:
Background of the Problem
What is Nutrition?
How Does Nutrition Affect The Human Body?
Asthma and its Effects
Nutritional Supplements
Uses of Nutritional Supplements That a Physician Should Know About
Treatment of Asthma
Why Is Asthma Under Diagnosed And Under Treated In The Elderly?
Statement of Problem: Effects of Nutritional Supplements on Asthma
Hypotheses for the Study
Definition of Terms
Importance of the Study - Nutritional Supplements and Asthma
Why should we study the effect of Nutritional Supplements on Asthma?
Research Questions for the Study
Methods of Research - Methodology
Procedure to Collect Data and Treatment of Data
Methods-Sample Selection and Sample Size
Ethics and Review
Conclusion

From the Paper
"Asthma is categorized as disease that has taken a toll on children, adolescents and elderly alike. It has symptoms that are easy to detect, and for such, treatment is usually always required. However, one thing to note here is the fact that Asthma is generally incurable and that it can only be controlled through drugs and medication, with proper and early diagnosis of asthma in the patient. (Mark, 2006)
"It is one the most common diseases in the United States and all over the world, with about approximately 20 million people affected with asthma in the United States only. In this, quite a large number are children. (Mark, 2006)"

Tags:asthmatic, vitamin, mineral

Abstract
This paper discusses abortion, showing all the key themes and issues currently affecting it. The introduction defines terms necessary for the paper such as "abortion", "human life" and "human person" and gives a history of abortion from ancient until modern times. It then puts forward the arguments of "pro-life" and "pro-choice", focusing on two unusual case studies that turn upside-down commonly held views on when abortion is or is not appropriate - one supporting abortion (a mother who simply did not want a child at her life stage) and another opposing abortion (a woman who was born after her mother was raped). It attempts to show through these examples that it is possible to eloquently argue either for or against abortion but that ultimately it is impossible to determine whether abortion is "right" or "wrong" and that each case needs to be judged on its individual merits.

From the Paper
"The Catholic Church also has inconsistencies regarding intra-uterine devices (IUD's) and its funeral and burial services. Most people believe that IUD's interfere with the implantation of fertilized ovum in the uterine wall. If this is correct, it means that IUD's terminate development after conception and therefore after a human person has been formed. This means that, technically, approximately 43% of American women have had an abortion. There have also been burial services and funerals held by the Roman Catholic Church for aborted fetuses. However, this has not generally been the case as fetuses have not been considered full persons by the Church to the extent of being worthy of a formal requiem mass or formal burial service."

Tags:choice, human, incest, life, person, rape

Abstract
The media has a large effect on society as a whole and there has been an increase in media exposure over the years. The thin, waif-like look is seen as the ideal, a standard for women to be measured against. The paper shows that women are under lots of pressure to conform to the ideals of society and the majority of women are on diets or have dieted at some point in their life. This leads to low self esteem and poor body image, which is a precipitating factor in eating disorders. This essay discusses whether the media is the catalyst for preoccupation with slimness and a major contributor to eating disorders in young women.

From the Paper
"The media is often quoted as a scapegoat for the increase in eating disorders. Linda Grant's opinion is that: "Women don't set out to become anorexic, they begin by thinking they're too fat because everywhere they go the media is telling them that they are right" (Barrett, 1997). This assumes that the causes of eating disorders are simply triggered by an individual feeling overweight, which is not the case. Eating disorders have many causes, some evidence suggests that an eating disorder can exist without this pathological fear of being overweight (Lai, 2000). If these effects of the media are obvious then why is it that only 1-3% of women suffer from an eating disorder? "

Tags:anorexia, bulimia

Abstract
This paper presents a detailed examination of Dorothy Johnson's behavioral system model. The writer explores the model itself and then uses case study examples to apply the theory to real life situations in a critical care nursing role. It presents the positive outcomes for nurses and family members, of using the model in critical care nursing.

Table of Contents:
Introduction
Johnson's Life
The Model
Case Study
Conclusion

From the Paper
"One of the most well known nursing theorists in modern history was Dorothy Johnson. Johnson ideas about the field of nursing and how that field relates to the care of individual patients, including her well known Behavior Model theory (Fruschwirth, 2000). The theory encompasses many of the medical systems in the human body and how they relate to behaviors of individuals to provide a measurable blueprint as to how to apply those functions and behaviors to the everyday practice of nursing. To understand how the Behavioral System Model was conceived and developed and how it pertains to today's nursing profession it is important to have a basic understanding of nursing itself and the life of Johnson."

Tags:critical, care, nursing, burden