Lipoproteins

Paper Summary:

This paper describes the different types of lipoproteins, their composition and their role in cholesterol metabolism including reverse cholesterol transport. It includes a table about the various lipoproteins, their apolipoproteins, size, composition and mechanism of delivery. It also includes a schematic diagram showing the metabolism of lipoproteins.

From the Paper:

"Based on their density as determined by ultracentrifugation, there are five major types of lipoproteins in the human blood, called chylomicrons, very low density lipoproteins (VLDL), intermediate density lipoproteins (IDL), low density lipoproteins (LDL), and high density lipoproteins (HDL) (Berneis and Krauss, 2002). The lipoproteins have different protein and lipid composition, sizes and physiological and pathological functions, as shown in Table 1. Chylomicrons, which consist mainly of triglycerides, redistribute dietary lipids that are absorbed in the intestine while the liver secretes lipids in the form of VLDL that serves for the extrahepatic deposition of free fatty acids after being processed enzymatically (Narayanaswami and Ryan, 2000)."

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