Abstract
An argumentative paper about the negative effects of human cloning. The author discusses the moral, ethical and religious issues that he believes outweigh the medical advances of cloning. Included is an overview of what cloning is and how it could effect society in the future.

From the Paper
"Human cloning is a controversial topic, the public regards it as inappropriate, while the leaders of certain scientific communities believe it is a sound practice that could be researched and used to benefit society. Human cloning is a form of genetic engineering, which most people consider morally wrong and, "Playing God". Through cloning an individual, you create an exact physical duplicate of that person, however, memories, personality and opinions are not recreated, and so differences do exist. Many pros and cons can be found when looking at cloning in depth, but it is my opinion that overall, it is not a beneficial procedure. There are just too many ethical issues that outweigh medical advances and prolonging life spans. A race has been started between scientists, everyone wants to be the first to clone an adult human, however with hopes of personal glorification and publicity, they have lost sight of the moral and religious issues at hand. Human cloning means creating a breed of people that have no flaws or imperfections, and since perfection does not exist, the clone could be nothing but a disappointment."

Tags:clones, ethics, genetics, twins

From the Paper
"THC has a range of physiological and psychological effects on the body. Typically, it produces a mild euphoric intoxication, a sense of well-being, alterations in sense of space and time. Quite likely, THC reduces anxiety and relaxes your tension while it intensifies your sense of sound, touch ,or taste, which often stimulates your appetite. It is suspected that THC has something to do with the Lateral Hypothalamus that control the appetite. For this reason, marijuana is employed as an appetite stimulant for patients with serious illnesses such as AIDS or terminal cancer who need to eat in order to survive. In addition, marijuana is also medically beneficial for pain relief, control of nausea and the treatment of asthma and glaucoma."

Tags:drugs, addictive, brain, cannabis, dopamine, fatty, hemp, metabolism, pot, receptor, reward, smoking, system, thc

Abstract
The paper begins by purifying beef heart and ends with a highly-quantitative analysis of the results of attempting to isolate the enzyme lactate dehydrogenase. It contains every aspect of a detailed biochemistry lab report. The paper contains complex quantitative analysis with supporting statistics. It also has scanned photographs of the gel electrophoresis.

From the Paper
"Lactate dehydrogenase (LDH) is a crucial enzyme that regulates lactate levels throughout the mammalian body. Proper LDH function is essential for a number of important biochemical pathways, including the Cori Cycle and glycolysis among others. Without it, the glycolytic cycle would come to a halt due to diminished nicotinamide adenine dinucleotide (NAD+) reserves, and the buildup of lactate would ultimately result in lactic acidosis-a potentially fatal affliction."

Tags:bovine, centrifugation, chromatography, electrophoresis

Abstract
The writer explains that in this experiment, lysozyme was purified from egg white solution into 24 fractions using gel column chromatography. The writer points out that the odd-numbered fractions were then assayed in order to determine the enzymatic activity of lysozyme, while the even-numbered fractions were assayed for total protein content, using the Bradford protein assay procedure. The writer notes that lysozyme is one of the most well-known enzymes, being abundant in mucus, tears, and albumen (commonly known as egg white).
The writer concludes that the purification of lysozyme from egg white was only somewhat successful since the estimated value of the molecular weight, 14.25 kDa, is practically the same as the known weight of 14.3 kDa. However, the specific activity, calculated at 400 units/mg, was significantly less than the expected specific activity of 25 000 units/mg of protein.

Outline:
Abstract
Introduction
Materials and Methods
Results
Calculations
Discussion
Conclusion

From the Paper
"Lysozyme is itself composed of 129 amino acids, including four disulfide bridges and three sets of alpha helices. The enzyme's active site consists of a long groove that can hold as many as six polysaccharides. According to past experiments, specific activity of lysozyme from egg white is approximately 25 000 units/mg. This is the expected result for this experiment. However, one factor that influences the specific activity is the actual column and type of chromatography being used, since accuracy differs among the different types of chromatographies. Therefore, some are able to purify enzymes better than others, giving a more accurate specific activity. In addition to obtaining the specific activity, molecular weight of the enzyme can be determined by comparing the fraction in which most of the enzyme eluted with the fractionation range."

Tags:protein, egg, white, calculations, fractions

Abstract
This paper is an examination of the mechanisms of colon tumorigenesis involving the mutation cluster region of the APC gene. There is an explanation of colon carcinogenesis including an analysis of the Wnt signaling pathway, the roles of the APC gene's different domains, "Knudon's two- hit hypothesis and the "just right" level of signaling theory. The paper also includes a critical discussion about the scientific arguments and research evidence that exists to challenge current understanding of the underlying mechanisms of colon tumorigenesis. One illustration is included which depicts the varying domains of the APC gene.

From the Paper
"Colorectal cancer is the third most common form of cancer and the second leading cause of death in the western world. Nearly 34,900 people are diagnosed with it in the U.K each year and about 16,000 of these die. About 15% of colorectal cancers are hereditary. Hereditary conditions are divided into two categories: the polyposis and the non polyposis types. Two hereditary conditions that have been identified are Familial Adenomatous Polyposis Coli (FAP) and Hereditary Non Polyposis Colorectal Cancer (HNPCC). The adenomatous polyposis coli (APC) gene is known to be mutated in all cases of FAP but this condition only accounts for less than 1% of colorectal cancer cases. The condition HNPCC results when mutation occurs in the DNA mismatch repair genes MSH2 and MLH-1 leading to microsatellite instability and defective DNA repair. Non inherited mutations of the APC gene have been detected in over 85% of the remaining sporadic colorectal cancers. "

Tags:Familial, Adenematous, Polyposis, Hereditary, non, polyposis, colon, cancer, Wnt-signally, pathway

Abstract
This paper discusses how ever since the ?Thalidomide? incidence last century there has been an ever-increasing amount of resources injected into optical isomeric research and in attaining pure enantiomeric products. It shows how due to different stereochemical characteristics, different isomers will have different interactions with biological receptors in the body, giving rise to different actions. A resultant undesirable effect is therefore inherently possible upon the consumption of chiral drugs, for that reason it is imperative that the end drug mixture is as entiomerically pure as possible. It describes the 3 basic methodologies for single enantiomers: chirality pool, kinetic resolution and asymmetric synthesis and examines the basis of and the techniques of separating them.

From the Paper
"One way of the use of chirality pool molecules merely requires the maintenance of pre-existing chirality throughout a synthesis, with transformation of other parts of the molecule by formation of new chemical bonds or inter-conversion of functional groups. Otherwise, utilising chirality pool can afford a so-called "control element" for the creation of new stereogenic centres by "substrate-directable" reactions. Such reactions may involve complete transfer of chirality from one region to another intra-molecularly.[1]"

Tags:assymetric, biocatalysis, catalysts, chiral, chirality, kinetic, racemate, racemisation, recrystallisation, resolution, sythons

Abstract
This paper analyzes St. Johns Wort (SJW), a common herbal treatment. It offers an insight into how its constituents affect us neurologically with its primary ingredients of hypericin, hyperflorin and various flavanoids and describes how, although SJW can be used for various treatments, the main condition that it is used for is depression. It provides a comparative study of conventional anti-depressive agents and their relative side effects and shows how the demand for herbal medicines today is rising at exponential rates, with an obvious advantage such as reductions in the number of side effects. It evaluates whether herbal medicines all that they claim to be and if they contain any profound pharmacological constituents or whether they give just a placebo effect.

From the Paper
"Herbal medicines are clearly mixtures of more than one active ingredient and in many instances, we are not sure which or how many constituents are pharmacologically important. Furthermore, in trying to acquire the mechanisms of action of plant extracts is often complicated even if we know the active ingredient because such extracts contain a wide range of pharmacologically active constituents that might work together to contribute to the pharmacological activity. [1] Our understanding is further dinted if the molecular basis of the disease under investigation is not well understood."

Tags:anti, depressants, hyperforin, hypericum, monoamine, noradrenaline, oxidase, placebo, prozac

Abstract
This paper looks at epilepsy and discusses the different types, symptoms, medication and social impacts as well as its treatment and aftercare. It includes basic understanding of the pathophysiology of the disease process and how drug actions and chemicals in the brain thought to contribute to the disease.

Outline
Disease Classification
Normal Physiology and the Effects of the Disease
Treatment for the Disease
Patient Care

From the Paper
"The symptoms of Epilepsy, in my opinion and using the aforementioned evidence, definitely reflect the effects of the disease on the "normal" physiological functioning of the body. The chaotic, unregulated neuronal discharge in the cortex seems to have, from a simplistic point of view, a direct and visible correlation with the chaotic events, muscular spasm and loss of involuntary functions e.g., Breathing, bladder control or swallowing. The complexities of diagnosis and detection of the areas of brain cortex responsible for the discharge are made somewhat easier by the use of EEG, this also simplifies diagnosis of each individual as well as identifying which strain they may have. Although Monton (1985) does state that EEG has its limitations and therefore requires clinical assessment to be used in conjunction with EEG for effective and accurate investigation and diagnosis."

Tags:absence, acid, aminobutyric, carbamazepine, clonic, epileptic, gamma, seizures, sodium, tonic, valproate

Abstract
This paper deals with how spots occur (inflamed lesions), and their subsequent bacterial growth. It gives details into how the effect of various concentrations of anti-bacterial facewashes affect the spread of bacteria. A thorough experimental aceptic technique is made reference to in this paper.

From the Paper
"A spot starts when a pore in the skin becomes blocked - usually with oil (sebum) and dead skin cells, which the skin produces. As the pore becomes blocked, it becomes infected with bacteria, which are normally present on the surface of the skin. These bacteria breakdown the oil and dead cells to form chemicals which cause swelling, redness and the formation of an "inflamed lesion" or a SPOT."

Tags:agar, anti, asceptic, bacteria, bacterial, clearing, coli, epidermis, inflamed, lesions, ph, spots, technique, temperature, zone

Abstract
This paper digs deeply into how aspirin and salbutamol were developed and also how they interact in the body from a heavy chemical and neurological perspective. It also gives a detailed overview into how, in general, pharmacueticals are developed using bronchodilars as an example. Also included are numerous diagrams in order to aid the reader comprehend the text.

From the Paper
"Since 400BC physicians prescribed a bitter powder extract from the willow bark tree to alleviate pain. In the middle of the 18th century two chemists by the name of Fontana and Brugnatelli extracted the active agent Salicin from the willow, and was then converted by Piria into Salicylic acid. Felix Hoffman a German chemist set about trying to synthesize salicylic acid."

Tags:adrenaline, adrenocepters, agonist, bark, compound, cox1, cox2, hoffman, industry, kolbe, meloxicam, pharmaceutical, phenol, salicylic, ventolin, willow